Amino acid sequences of core histone and their kinds, indicating websites of put up-translational modification. The exception to the rule is the DOT1 household, members of which methylate K79 in the globular area of histone H3 and which are structurally not associated to SET-domain proteins 4 - 6 Latest work suggests that SET-area-containing proteins methylate a couple of proteins in addition to histones (see later)